Premium
An Overview of the Diagnostic Considerations in Polycystic Ovarian Syndrome a
Author(s) -
CROWLEY WILLIAM F.,
HALL JANET E.,
MARTIN KATHRYN A.,
ADAMS JUDITH,
TAYLOR ANN E.
Publication year - 1993
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1993.tb43871.x
Subject(s) - polycystic ovary , medicine , bioinformatics , neuroscience , psychology , biology , endocrinology , diabetes mellitus , insulin resistance
The past ten years have been particularly exciting with regard to the elucidation of the pathophysiology of PCOS. It appears that PCOS is about to yield some of its mysteries and to have some of its discrete subsets defined, as Cushing syndrome did 50 years ago. However, future studies of PCOS will require a complex interplay of clinical investigation, molecular and genetic probes, increasingly refined anatomic observations, and fundamental neuroendocrine studies. Each observer has a bias, which must be acknowledged in his/her studies. However, a true synthesis of the abnormalities characteristic of PCOS must continually be sought, for only through a comprehensive view of this syndrome will we come to understand its true pathophysiology; and only then can rational therapies be designed.