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Ion Channel Activity and Transmembrane Signaling in Lymphocytes a
Author(s) -
DAMJANOVICH SÁNDOR,
PIERI CARLO,
TRÓN LAJOS
Publication year - 1992
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1992.tb49123.x
Subject(s) - extracellular , ion channel , potassium channel , light gated ion channel , transmembrane protein , microbiology and biotechnology , chemistry , biophysics , intracellular , signal transduction , voltage gated ion channel , transmembrane domain , channel (broadcasting) , ligand gated ion channel , biochemistry , biology , membrane , computer science , receptor , telecommunications
Transmembrane signalling refers to the process of transfer of information from the extracellular world into the intracellular space. The information is transduced through several possible pathways. The significance of cell surface dynamics, ion channel activity and drug effects are discussed in the signal transmission, with special reference to Na+ channels and the Ca2+ sensitive potassium channels.