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Occurrence of CGRP Receptors on Dedifferentiated Smooth Muscle Cells from Media of Rat Thoracic Aorta a
Author(s) -
CONNAT JEANLOUIS,
THIEVENT ALAIN,
CARRIER NATHALIE,
HUGGEL HANSJÖRG
Publication year - 1992
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1992.tb22795.x
Subject(s) - smooth muscle , calcitonin gene related peptide , receptor , thoracic aorta , aorta , chemistry , anatomy , microbiology and biotechnology , medicine , endocrinology , biology , neuropeptide
Autoradiographic studies with [125I]-CGRP did not demonstrate receptors on sections from two different regions of 5-week-old rat aorta (of both sexes). By contrast, cultured smooth muscle cells isolated from similar aortic media and passaged 5 to 7 times exhibited specific binding.