Premium
Calcitonin Gene—Related Peptide in the Brain
Author(s) -
SARIA A.,
BERNATZKY G.,
HUMPEL C.,
HARING C.,
SKOFITSCH G.,
PANKSEPP J.
Publication year - 1992
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1992.tb22765.x
Subject(s) - calcitonin gene related peptide , calcitonin , gene , peptide , medicine , chemistry , biology , genetics , neuropeptide , biochemistry , receptor
CGRP in the amygdala is concentrated in an area close to the central nucleus. High potassium releases CGRP, and this release, as well as the tissue concentration of CGRP in the amygdala, can be influenced by neuroleptic drugs. Both molecular forms, alpha- and beta-CGRP, are present in the amygdala in a ratio of approximately 3:1. CGRP influences social behavior in chicken. Therefore, CGRP may have a prominent role in psycho-behavioral function and may be a target for action and/or side effects of antipsychotic drugs.