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A Randomized Trial of Dietary Intervention with Essential Fatty Acids in Patients with Categorized Cysts
Author(s) -
MANSEL R. E.,
HARRISON B. J.,
MELHUISH J.,
SHERIDAN W.,
PYE J. K.,
PRITCHARD G.,
MADDOX P. R.,
WEBSTER D. J. T.,
HUGHES L. E.
Publication year - 1990
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1990.tb17819.x
Subject(s) - evening primrose oil , placebo , medicine , evening , randomized controlled trial , cyst , placebo group , surgery , pathology , physics , alternative medicine , astronomy
Two hundred women with breast cysts proven by aspiration were entered into a randomized double-blind trial of Efamol (evening primrose oil) at a dose of 6 capsules daily or equivalent placebo dose for a year. Cysts were categorized by initial electrolyte composition, and follow-up continued for 1 year posttherapy. Recurrent cyst formation in the first year was slightly (but not significantly) lower in the Efamol group compared with the placebo-treated group. The Efamol treatment was well tolerated as the dropout rate was only 7% and equal in both the active and placebo groups. The initial electrolyte composition did not predict for cyst recurrence.