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First Available Results of Long‐Term Carcinogenicity Bioassay on Detergency Zeolites (MS 4A and MS 5A) a
Author(s) -
Cesare Maltoni,
Franco Minardi
Publication year - 1988
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1988.tb30189.x
Subject(s) - library science , citation , chemistry , toxicology , computer science , biology
Long-term experimental carcinogenicity bioassay was carried out on MS 4A and MS 5A zeolites. The materials were tested on Sprague-Dawley rats by intraperitoneal, intrapleural, and subcutaneous injection of 25 mg in 1 ml of H2O. The results of this bioassay (the onset of one peritoneal mesothelioma in a male rat treated by intraperitoneal injection of zeolite MS 4A) calls for further and more sophisticated tests on zeolites used as detergents.