Premium
Mechanisms of Virus‐Induced Demyelination and Remyelination a
Author(s) -
RODRIGUEZ MOSES
Publication year - 1988
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1988.tb27066.x
Subject(s) - remyelination , multiple sclerosis , myelin , demyelinating disease , pathogenesis , demyelinating disorder , isolation (microbiology) , viral pathogenesis , viral infection , myelin sheath , neuroscience , virology , virus , biology , immunology , medicine , viral replication , central nervous system , bioinformatics
Viral models of demyelination and remyelination provide important clues to the pathogenesis of multiple sclerosis. Determining the precise viral polypeptides recognized by T cells during the demyelinating process will be important in understanding the mechanisms of viral-induced myelin destruction. Isolation, purification, and characterization of factors that promote remyelination and proliferation of oligodendrocytes may provide hope in the treatment of patients with chronic demyelinating disorders.