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Hypothalamic Neurotransmitters in Relation to Normal and Disturbed Eating Patterns a
Author(s) -
LEIBOWITZ SARAH F.
Publication year - 1987
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1987.tb36205.x
Subject(s) - neurochemical , neuroscience , monoamine neurotransmitter , organism , food intake , psychology , energy homeostasis , endocrine system , neuropeptide , biology , medicine , endocrinology , serotonin , hormone , paleontology , receptor , obesity
An integrated hypothesis for explaining eating behavior must consider the organism as a whole, the multiple brain neurotransmitters and structures involved, and the diverse variables that have impact on the expression of the behavior. In this review, we will examine a variety of brain monoamines and neuropeptides, in terms of their impact on eating, and also relate these neurochemical systems to peripheral autonomic and endocrine functions. We will propose how these central and peripheral systems may interact under normal and generally stable conditions, as well as how they may help to maintain energy or nutritional homeostasis under stressful conditions, in particular, food deprivation.