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Using Fault Analysis Methods to Improve Bioreactor Safety
Author(s) -
III RAYMOND P. JEFFERIS,
SCHLAGER STEPHEN T.
Publication year - 1986
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1986.tb26483.x
Subject(s) - bioreactor , reliability engineering , computer science , biochemical engineering , chemistry , environmental science , engineering , organic chemistry
A simplified fault analysis algorithm has been described and applied to the analysis of containment loss in a model bioreactor system. Using approximate data for component failure rates, the relative merits of three proposed operating regimes were evaluated by means of a computer program that implements the algorithm described. With the data given, operator error is shown to be the dominant cause of possible failure in the proposed system. In view of these results, the simplified algorithm appears useful for the comparative evaluation of various design proposals in simple systems.