Premium
Genetic Control of Macrophage Responses a
Author(s) -
FURTH R.,
SLUITER W.,
DISSEL J. T.
Publication year - 1986
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1986.tb18476.x
Subject(s) - phagocytosis , monocyte , macrophage , intracellular , bacteria , chemistry , microbiology and biotechnology , biology , immunology , biochemistry , genetics , in vitro
A short review of current concepts concerning the origin and kinetics of monocytes and macrophages is given, and the humoral regulation of monocyte production by FIM, a factor synthesized and secreted by macrophages, is discussed. Genetic control of the responsiveness of monocyte precursors to FIM and that of the phagocytosis and intracellular killing of bacteria is dealt with.