Premium
Use of a Modified Test System to Determine Early Pregnancy Factor (EPF) Levels in Patients with Normal First Trimester Pregnancy and after Therapeutic Abortion
Author(s) -
TINNEBERG H.R.,
STAVES R.P.,
HANF V.,
SCHOLZ W.,
SEMM K.,
METTLER L.
Publication year - 1985
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1985.tb37564.x
Subject(s) - pregnancy , abortion , medicine , obstetrics , early pregnancy factor , first trimester , gynecology , fetus , gestation , biology , genetics
Human pregnancy can be recognized as early as 48 hours after conception using the rosette inhibition test (RIT) to detect early pregnancy factor (EPF). A modification of the test as originally described by Morton et al. is demonstrated using a monoclonal pan T-cell antibody. Studies were performed to investigate the relationship between EPF levels during normal first trimester intact pregnancies and therapeutic abortions. The change in EPF levels is compared with those of hormones after interrupted pregnancy.