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Co‐existence of Cholecystokinin‐ or Gastrin‐like Peptides with Other Peptides in the Hypophysis and the Hypothalamus a
Author(s) -
VANDERHAEGHEN JJ.,
GOLDMAN S.,
LOTSTRA F.,
REETH O. VAN,
DESCHEPPER C.,
ROSSIER J.,
SCHIFFMANN S.
Publication year - 1985
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1985.tb29928.x
Subject(s) - neuropathology , humanities , medicine , art , disease
The presence of cholecystokinin and gastrin has been reported in the hypothalamohypophyseal system. These peptides present a peculiar distribution in the hypothalamic nuclei, the median eminence, and the neurohypophysis. CCK and gastrin have close relationships with other peptides like oxytocin, CRF, vasopressin, and the enkephalins; these relationships vary in different projecting areas and in different types of hypothalamic neurons. The functional role of G-CCK in neurosecretion seems to be linked to the role of these closely associated peptides and certainly deserves further investigation.