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Anatomical Studies of Cholecystokinin in Neurons and Pathways Involved in Neuroendocrine Regulation
Author(s) -
KISS JOZSEF Z.
Publication year - 1985
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1985.tb29914.x
Subject(s) - median eminence , oxytocin , cholecystokinin , neuropeptide , secretion , endocrinology , neuroscience , medicine , hypothalamus , biology , hormone , magnocellular cell , vasotocin , receptor
A CCK-like substance has been identified in two distinct neuronal systems of the PVN which are both involved in neuroendocrine regulation. The CCK parvicellular neurons are potentially involved in the regulation of adenohypophyseal hormone secretion through projections to the external zone of the median eminence. CCK immunoreactivity was also identified in the magnocellular-neurohypophyseal system, exclusively in oxytocinergic neurons. Thus, CCK might participate in the modulation of oxytocin secretion.