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Atherosclerosis as an Inflammatory Process
Author(s) -
SCHWARTZ COLIN J.,
VALENTE ANTHONY J.,
SPRAGUE EUGENE A.,
KELLEY JIM L.,
SUENRAM C. ALAN,
ROZEK MARIUS M.
Publication year - 1985
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1985.tb11849.x
Subject(s) - process (computing) , medicine , computer science , operating system
In this brief review, we have addressed the roles of the monocyte-macrophage in atherogenesis, with emphasis on the recruitment to the arterial wall. We have presented summary data on the SMC-derived chemoattractant protein and also on the temporal evolution of monocyte-derived macrophages into cholesteryl ester-rich foam cells. The concept of atheroma as an inflammatory process has also been discussed.