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Genetic Analysis of Mammalian Spermatogenesis: Use of the t Complex in the Mouse in Studies of Spermatogenesis and Sperm Function a
Author(s) -
OLDSCLARKE PATRICIA
Publication year - 1984
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1984.tb38287.x
Subject(s) - spermatogenesis , citation , sperm , function (biology) , medicine , biology , library science , genetics , andrology , computer science
Our observations suggest that sperm populations from the caudae epididymides of tw32/+ mice undergo hyperactivation in vitro sooner and to a much greater extent than do sperm populations from congenic +/+ mice: (1) epididymal tw32/+ sperm populations become significantly less progressive in vitro than do +/+ sperm populations; (2) low (0.1 mM) levels of Ca2+ prevent this loss of progressiveness; (3) epididymal tw32/+ sperm populations have trajectories and progressiveness values similar to both +/+ and tw32/+ oviductal sperm populations; (4) an inhibitor of capacitation inhibits the loss of progressiveness. This divergence from normal motility may be the result of expression of one of the factors involved in transmission distortion of the t complex.