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Immune Responses to Myelin Antigens in Multiple Sclerosis a
Author(s) -
LISAK ROBERT P.,
ZWEIMAN BURTON,
BURNS AJMES B.,
ROSTAMI ABDOLMOHAMMAD,
SILBERBERG DONALD H.
Publication year - 1984
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1984.tb14793.x
Subject(s) - multiple sclerosis , immune system , antigen , myelin , immunology , myelin sheath , neuroscience , biology , central nervous system
Multiple sclerosis is considered to be a putative immunopathologic disease and there has been considerable effort over the years to prove an autoimmune etiology for it. To date, the evidence is all indirect and there is no proof of either antibody and/or cell-mediated hypersensitivity to any single identifiable CNS constituent whether a constituent of normal CNS or specific to the CNS of MS patients.