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T‐ AND B‐CELL MEMORY ON MUCOSAL SURFACES
Author(s) -
Ganguly R.,
Waldman R. H.
Publication year - 1983
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1983.tb26902.x
Subject(s) - booster (rocketry) , immune system , immunological memory , immunization , antigen , immunology , memory cell , biology , b cell , immunity , antibody , physics , transistor , quantum mechanics , astronomy , voltage
The secretory immune system exhibits memory responses in both B- and T-cell systems. Booster immunization mediates rapid activation of immune lymphocytes that may be important for host protection. Local memory responses may be generated following application of the antigen systemically or at other distant mucosal sites. The dichotomy between the systemic and local immune systems could be overcome, at least partially, in memory responses, depending upon the route and amount of antigen employed for the booster immunization.