Premium
STUDIES OF Ca 2+ RELEASE FROM SARCOPLASMIC RETICULUM *
Author(s) -
MacLennan David H.,
Shoshan Varda,
Wood Donald S.
Publication year - 1982
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1982.tb25769.x
Subject(s) - endoplasmic reticulum , chemistry , biophysics , membrane , quercetin , biochemistry , biology , antioxidant
S ummary Our studies of Ca 2+ release have shown that three classes of compounds—quercetin, which inhibits Ca 2+ release by reversal of the Ca 2+ pump, H + ionophores and DCCD, which affect proton gradients, and lipophilic anions, which act to oppose a separation of membrane surface charges‐all have potential in probing the mechanism of Ca 2+ release from sarcoplasmic reticulum.