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ANTIGENIC RELATIONSHIPS AMONG VARIOUS INTERFERON SPECIES
Author(s) -
Kawade Y.,
Yamamoto Y.,
Fujisawa J.,
Watanabe Y.
Publication year - 1980
Publication title -
annals of the new york academy of sciences
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1980.tb20644.x
Subject(s) - interferon , antigen , biology , virology , immunology
Mouse L-cell interferon consists of two antigenically distinct species, F (22 to 24K) and S(32 to 40K). Various type I mouse interferons, regardless of lymphoid or nonlymphoid origin, likewise consist of two species, whose antigenicities are indistinguishable from the two L-cell interferons. Interferon F was found to be completely neutralizable by an antiserum against human leukocyte interferon, suggesting a structural similarity between the important species of human and mouse interferons.