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PENICILLAMINE IN THE THERAPY OF HEREDITARY MUSCULAR DYSTROPHY IN CHICKENS *
Author(s) -
Milhorat John H.,
Milhorat Ade T.
Publication year - 1979
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1979.tb56550.x
Subject(s) - citation , muscular dystrophy , library science , medicine , gerontology , computer science
This was a brief 6-month study of the possible value of penicillamine in adult chickens with hereditary muscular dystrophy. Detailed histologic investigation of various parameters of muscle architecture yielded no evidence of significant therapeutic effect. Several serious toxic symptoms were noted. It is suggested that in muscular dystrophy, a disease in which the main feature is profound alteration of muscle structure, histologic studies may be the best means of documenting response to therapeutic agents.