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PLASMA ACTH LEVELS IN STRESSED AND NONSTRESSED ADRENALECTOMIZED RATS
Author(s) -
RuhmannWennhold Ann,
Nelson Don H.
Publication year - 1977
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1977.tb41877.x
Subject(s) - salt lake , citation , annals , library science , medicine , psychology , history , classics , computer science , geology , paleontology , structural basin
Following adrenalectomy there is a triphasic response of ACTH secretion characterized by an initial high rise immediately following the adrenalectomy, secondary to the stress of the procedure. This is followed by a fall to resting ACTH secretion until a steady state is reached 1 to 2 weeks following adrenalectomy at levels about 10 times normal. The ability to respond to stress with increased ACTH secretion is not lost at any time following adrenalectomy.