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A PRELIMINARY REPORT ON A STUDY OF SERUM ALPHA‐1‐ANTITRYPSIN AND IMMUNOGLOBULIN LEVELS IN LEPROMATOUS LEPROSY
Author(s) -
Çelikoǧlu Seyhan I.,
Göksel Fahir M.,
Bilgin Türkan
Publication year - 1976
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1976.tb47023.x
Subject(s) - lepromatous leprosy , antibody , leprosy , immunology , immunoglobulin a , medicine , alpha (finance) , gamma globulin , immunoglobulin g , construct validity , nursing , patient satisfaction
IgG, IgA, and IgM immunoglobulins and alpha-1-antitrypsin globulin in sera from 30 patients with lepromatous leprosy were determined and compared with 30 age- and sex-matched healthy controls. Mean levels of IgG, IgM, IgA, and alpha-1-antitrypsin were significantly elevated in the sera of lepromatous leprosy patients in comparison with levels found in normal subjects. Statistical analysis of the relationships between levels of alpha-1-antitrypsin and immunoglobulins in the sera of lepromatous leprosy patients and controls revealed no correlation. It is therefore concluded that factors responsible for concentrations of immunoglobulins and alpha-1-antitrypsin are independent of each other in patients with lepromatous leprosy.