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PRELIMINARY STUDIES ON AFFINITY LABELING OF THE TUBULIN‐COLCHICINE BINDING SITE *
Author(s) -
Bryan Joseph
Publication year - 1975
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1975.tb19204.x
Subject(s) - citation , library science , annals , classics , chemistry , philosophy , art , computer science
The present results argue that irradiation of a colchicine-tubulin complex at 366 nm results in destruction of the binding site and the labeling of a small molecule soluble in chloroform-methanol.