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CARDIAC EFFECTS OF INTRACORONARY ARTERIAL INJECTIONS OF NICOTINE *
Author(s) -
Bellet Samuel,
West James W.,
Guzman Santiago V.
Publication year - 1960
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1960.tb32629.x
Subject(s) - medicine , general hospital , library science , family medicine , computer science
The purpose of this study was to determine the cardiac effects of nicotine by direct coronary artery injection. This method has the advantage of elucidating certain direct cardiac effects independent of systemic changes. The procedure previously described from this laboratory involves the ability to inject minute amounts of drugs or dye into various coronary branches of dogs without opening their chests or interfering with perivascular nerves.'*2