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CHLOROTHIAZIDE IN HYPERTENSIVE AND NORMOTENSIVE PATIENTS
Author(s) -
Freis Edward D.,
Wanko Annemarie,
Wilson Ilse M.,
Parrish Alvin E.
Publication year - 1958
Publication title -
annals of the new york academy of sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.712
H-Index - 248
eISSN - 1749-6632
pISSN - 0077-8923
DOI - 10.1111/j.1749-6632.1958.tb54619.x
Subject(s) - chlorothiazide , medicine , cardiology , diuretic
This was one of Freis's first attempts to evaluate chlorothiazide, a new diuretic that acted to increase the excretion of water and salt, and therefore reduced fluid in blood volume and decreased blood pressure. Here, along with several colleagues from the Veterans Administration and Georgetown University, he recognized the promise that this antihypertensive agent held, noting that chlorothiazide was an "effective and well-tolerated" treatment.