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Oromandibular dystonia questionnaire (OMDQ‐25): a valid and reliable instrument for measuring health‐related quality of life
Author(s) -
Merz R.I.,
Deakin J.,
Hawthorne M.R.
Publication year - 2010
Publication title -
clinical otolaryngology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.914
H-Index - 68
eISSN - 1749-4486
pISSN - 1749-4478
DOI - 10.1111/j.1749-4486.2010.02194.x
Subject(s) - medicine , quality of life (healthcare) , cronbach's alpha , botulinum toxin , observational study , physical therapy , discriminant validity , reliability (semiconductor) , family medicine , psychometrics , internal consistency , clinical psychology , surgery , nursing , power (physics) , physics , quantum mechanics
Clin. Otolaryngol. 2010, 35 , 390–396 Objective: To develop and validate a disease‐specific instrument to measure health‐related quality of life in patients with oromandibular dystonia. Design: Prospective, cross‐sectional observational study. Setting: Tertiary referral clinic, North East England, UK. Methods: The Oromandibular Dystonia Questionnaire (OMDQ‐25) was evaluated in a group of 30 patients for psychometric properties, including its sensitivity to change after Botulinum Toxin A treatment. Comparison to a generic instrument was enabled using the Glasgow Health Scale Inventory and the Glasgow Benefit Inventory (GBI). Results: Item generation passed tests for scaling assumptions. Reliability was proven (Cronbach’s α > 0.78; test‐retest > 0.9) and validity supported with both convergent validity and discriminant validity. Sensitivity to change after Botulinum Toxin A treatment was established for all subscales ( P ≤ 0.005), and in comparison with the GBI, all subscales showed large effect sizes. Conclusion: The Oromandibular Dystonia Questionnaire (OMDQ‐25) is the first reliable and valid instrument to measure health‐related quality of life in patients with oromandibular dystonia.