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Circulating natriuretic peptide concentrations in hyperthyroid cats
Author(s) -
Menaut P.,
Connolly D. J.,
Volk A.,
Pace C.,
Luis Fuentes V.,
Elliott J.,
Syme H.
Publication year - 2012
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2012.01301.x
Subject(s) - medicine , cats , natriuretic peptide , creatinine , thyroid , renal function , thyroid function , endocrinology , clinical significance , blood pressure , free thyroxine , heart failure
OBJECTIVES To assess the influence of thyroid function on natriuretic peptide concentration in hyperthyroid cats before and after treatment.METHODS Serum natriuretic peptide concentration was measured in 61 hyperthyroid cats recruited from first‐opinion clinics before and after treatment.RESULTS Following successful treatment, total thyroxine, heart rate, systolic blood pressure and packed cell volume all decreased and bodyweight and creatinine concentrations increased. Furthermore, a significant (P < 0·001) decline in NT‐proBNP concentration but not NT‐proANP was identified.CLINICAL SIGNIFICANCE Thyroid function has a modest but significant effect on NT‐proBNP concentration. Thyroid status should be taken into account when interpreting NT‐proBNP concentrations in cats.