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Presumed brain infarctions in two dogs with systemic leishmaniasis
Author(s) -
JoséLópez R.,
Fuente C. De,
Añor S.
Publication year - 2012
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2012.01259.x
Subject(s) - medicine , leishmania infantum , canine leishmaniasis , pathology , leishmania , leishmaniasis , magnetic resonance imaging , amastigote , vasculitis , visceral leishmaniasis , radiology , disease , parasite hosting , world wide web , computer science
Clinical signs and magnetic resonance imaging findings of multiple brain infarcts in two dogs infected with Leishmania spp. are reported. Clinical signs of intracranial dysfunction were peracute and there was no further deterioration. Magnetic resonance images of the brain were consistent with multifocal, non‐haemorrhagic, ischaemic lesions. Routine serum biochemistry revealed hyperproteinaemia and hyperglobulinaemia. Serum antibody titres were highly positive for Leishmania infantum and Leishmania amastigotes were seen within bone marrow macrophages in both cases. Canine leishmaniasis can cause cerebrovascular alterations, such as vasculitis, that might predispose dogs to brain infarcts.