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Subcutaneous pre‐anaesthetic medication with acepromazine–buprenorphine is effective as and less painful than the intramuscular route
Author(s) -
Gurney M.,
Cripps P.,
Mosing M.
Publication year - 2009
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2009.00786.x
Subject(s) - medicine , acepromazine , anesthesia , propofol , sedation , intramuscular injection , buprenorphine , sedative , surgery , opioid , heart rate , receptor , blood pressure
O bjectives : To compare reaction to injection, sedation and propofol induction dose in dogs receiving acepromazine–buprenorphine pre‐anaesthetic medication by the intramuscular or subcutaneous routes.M ethods : Fifty‐two client owned dogs of American Society of Anesthesiologists grade I or II anaesthetised for diagnostic imaging. Dogs were randomly assigned to receive acepromazine 0·03 mg/kg and buprenorphine 0·02 mg/kg either intramuscular or subcutaneous. Reaction to injection was scored. Sedation was compared before and one hour after pre‐anaesthetic medication. Propofol was administered in 1 mg/kg incremental injections until tracheal intubation was achieved. Total propofol dose was recorded.R esults : Reaction to injection was significantly greater (P=0·009) in the intramuscular group compared to the subcutaneous group. Sedation scores were not significantly different (P=0·523) between the intramuscular and the subcutaneous group. There was no statistically significant difference in propofol dose for induction (P=0·7).Clinical Significance: Acepromazine–buprenorphine pre‐anaesthetic medication provides a similar degree of sedation whether administered by the intramuscular or subcutaneous route. The intramuscular route is more painful compared to the subcutaneous route.