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Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog
Author(s) -
Russell N. J.,
Irwin P. J.,
Hopper B. J.,
Olivry T.,
Nicholls P. K.
Publication year - 2008
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2008.00253.x
Subject(s) - medicine , vasculitis , pulmonary hypertension , juvenile , cardiology , disease , biology , genetics
A five‐month‐old female Jack Russell terrier was presented for investigation of acute lethargy, anorexia, coughing, respiratory distress and weakness. Examination findings included cyanosis, a grade 3 of 6 systolic heart murmur and prolonged capillary refill time. Radiography and echocardiography revealed severe pulmonary hypertension, cor pulmonale and right‐sided heart failure. Indirect measurement of the systolic pulmonary artery pressure estimated pressures over 100 mmHg. Despite treatment the patient died. Post‐mortem examination did not identify a congenital cardiovascular anomaly. Histopathology confirmed acute necrotising pulmonary arteritis and immunohistochemistry failed to identify any immune complex or complement deposition.