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Cerebellar cortical abiotrophy in Lagotto Romagnolo dogs
Author(s) -
Jokinen T. S.,
Rusbridge C.,
Steffen F.,
Viitmaa R.,
Syrjä P.,
De Lahunta A.,
Snellman M.,
Cizinauskas S.
Publication year - 2007
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2006.00298.x
Subject(s) - granular layer , medicine , cerebellar cortex , pathological , purkinje cell , pathology , lesion , cerebellum , anatomy , cortex (anatomy) , neuroscience , biology
This case report documents two pathological variations of potentially inherited, cerebellar cortical abiotrophy in two unrelated Lagotto Romagnolo breed dogs. The first dog had an atypical lesion in the cerebellar cortex with depletion of cerebellar granular cell layer and sparing of the Purkinje cell layer. The second case had degenerative changes in both Purkinje and granular cell layers. The clinical picture was similar in both cases presented, although the severity of the signs of cerebellar dysfunction varied.