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Lymphocytic‐plasmacytic thyroiditis and glomerulonephritis in a boxer
Author(s) -
Mansfield C. S.,
Mooney C. T.
Publication year - 2006
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2006.00047.x
Subject(s) - medicine , lethargy , membranoproliferative glomerulonephritis , thyroiditis , pathology , etiology , thyroid , glomerulonephritis , immunology , kidney
An 18‐month‐old boxer was presented for investigation of profound lethargy, and primary hypothyroidism was diagnosed. A strong antithyroglobulin antibody titre was also present, indicating lymphocytic (immune‐mediated) thyroiditis as the cause of hypothyroidism. A concurrent protein‐losing glomerulonephropathy was also detected, although the aetiology could not be determined at initial presentation. Thyroid replacement and dietary therapy were prescribed. The dog improved clinically for approximately 12 months when it was re‐presented with poorly controlled hypothyroidism and renal failure. Postmortem examination confirmed the presence of lymphocytic‐plasmacytic thyroiditis, in conjunction with membranoproliferative glomerulonephritis and renal failure.