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Nephrotic syndrome associated with administration of sulfadimethoxine/ ormetoprim in a dobermann
Author(s) -
Vasilopulos R. J.,
Mackin A.,
Lavergne S. N.,
Trepanier L. A.
Publication year - 2005
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2005.tb00315.x
Subject(s) - medicine , nephrotic syndrome , sulfadimethoxine , discontinuation , drug , intensive care medicine , pediatrics , pharmacology , chemistry , chromatography
This case report describes sulphonamide‐induced nephrotic syndrome in a young dobermann dog. The clinical signs and laboratory abnormalities resolved shortly after discontinuation of the sulphonamide antibiotic and with generalised supportive care. Since nephrotic syndrome typically carries a guarded prognosis in veterinary medicine and is poorly responsive to therapy, a thorough drug history should be an important part of the investigation of any animal with a protein‐losing nephropathy.