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Progressive myoclonus epilepsy in a beagle
Author(s) -
Gredal H.,
Berendt M.,
Leifsson P. S.
Publication year - 2003
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2003.tb00113.x
Subject(s) - myoclonic jerk , medicine , myoclonus , lafora disease , progressive myoclonus epilepsy , beagle , epilepsy , depression (economics) , brain biopsy , pediatrics , disease , anesthesia , pathology , psychiatry , biochemistry , chemistry , phosphorylation , phosphatase , economics , macroeconomics
A nine‐year‐old, neutered female beagle was presented with a history of progressive myoclonic jerks. Clinical signs included mental depression and paroxysmal jerks of the head and forelimbs, apparently elicited by changes in light, noise or movements. Electroencephalographic findings were in accordance with myoclonus epilepsy. Postmortem histopathological findings included multiple periodic acid‐Schiff‐positive inclusion bodies throughout the central nervous system, but especially in the cerebellum, confirming the suspected diagnosis of Lafora's disease.