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Use of proligestone in the management of three German shepherd dogs with pituitary dwarfism
Author(s) -
Knottenbelt C. M.,
Herrtage M. E.
Publication year - 2002
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2002.tb00051.x
Subject(s) - medicine , dwarfism , german shepherd dog , acromegaly , adverse effect , endocrinology , surgery , growth hormone , biochemistry , chemistry , hormone , gene
Three German shepherd dogs were diagnosed with pituitary dwarfism and subsequently treated with proligestone. Treatment resulted in development of an adult hair coat, increased bodyweight and elevated insulin‐like growth factor‐1 concentration. Two dogs received thyroid supplementation during proligestone therapy. Adverse effects (cystic endometrial hyperplasia and acromegaly) were reported in two cases. No side effects were reported in the remaining case. This is the first report of the use of proligestone in the management of pituitary dwarfism.