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Cerebellar cortical abiotrophy in a beagle
Author(s) -
Kent M.,
Glass E.,
DeLahunta A.
Publication year - 2000
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2000.tb03210.x
Subject(s) - beagle , puppy , medicine , cerebellum , pathology , cerebellar diseases , lesion , histopathology , histopathological examination , anatomy , biology , ecology
A beagle puppy was presented with clinical signs indicative of a cerebellar disease. Histopathological evaluation of the cerebellum revealed a diffuse degenerative cortical lesion. The clinical history and the histopathological findings are consistent with a neonatal cerebellar abiotrophy. Furthermore, the breeding history supports the hypothesis of an inherited genetic disorder that is, most likely, an autosomal recessive trait.