Premium
Factors influencing the incidence and prognosis of canine mammary tumours
Author(s) -
Alenza M. D. Perez,
Pena L.,
Castillo N. del,
Nieto A. I.
Publication year - 2000
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.2000.tb03203.x
Subject(s) - medicine , grading (engineering) , incidence (geometry) , mammary gland , pathology , breast cancer , oncology , cancer , physics , civil engineering , optics , engineering
Factors relating to the incidence of canine mammary tumours are reviewed. Increased age, intact status or ovariectomy after 2.5 years of age, as well as progestagen treatment, can all lead to an increased risk of mammary neoplasia in the bitch. In addition, obesity early in life, and a habitual diet based on home‐made food (rich in beef and pork, and poor in chicken) as opposed to commercial food, are also associated with the occurrence of mammary tumours. Other aspects related to incidence are also discussed. Increased age at diagnosis, invasive growth (fixed to adjacent tissues), large tumour size, ulceration of skin, and axillary or inguinal node involvement are clinical parameters associated with a low chance of survival after surgical excision of mammary tumours. Histological typing and grading of the tumour allows the establishment of a prognosis, which is poor where there is tumour proliferation as measured by S‐phase fraction determination and Ki‐67 immunostaining.