Premium
Thrombosis of the portal vein in a miniature schnauzer
Author(s) -
Espiñeira M. M. Díaz,
VinkNooteboom M.,
Ingh T. S. G. A. M.,
Rothuizen J.
Publication year - 1999
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1999.tb03016.x
Subject(s) - medicine , cirrhosis , prednisolone , portal vein thrombosis , abdominal ultrasonography , jaundice , thrombus , thrombosis , gastroenterology , hepatitis , pathology , radiology , ultrasonography
A miniature schnauzer with a history of apathy, anorexia and jaundice was presented to the Utrecht University Clinic for Companion Animals. Abnormal laboratory findings included highly increased levels of total bile acids and alkaline phosphatase, and hyponatraemia. Abdominal ultrasonography revealed that the right side of the liver was enlarged and the left side was small, together with a thrombus in the portal vein. Biopsies from the right side of the liver demonstrated subacute to chronic active hepatitis, for which the dog was treated with prednisolone (1 mg/kg/day for four weeks). No improvement was observed and the owner requested euthanasia. At necropsy the left lobes of the liver were found to be small and firm, while the right lobes were large and soft. There were two thrombi in the portal vein. Microscopic examination revealed chronic active hepatitis and cirrhosis.