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Treatment of acquired myasthenia gravis associated with thymoma in two dogs
Author(s) -
Rusbridge C.,
White R. N.,
Elwood C. M.,
Wheeler S. J.
Publication year - 1996
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1996.tb02419.x
Subject(s) - medicine , myasthenia gravis , thymoma , dermatology , pathology
Two cases of myasthenia gravis associated with thymoma are reported. Both were female German shepherd dogs and the thymoma was surgically resected. Aspiration pneumonia secondary to persistent megaoesophagus was a complication in both cases. The myasthenia gravis did not resolve, but there was a more satisfactory control of clinical signs with anticholinesterase treatment. Corticosteroid therapy was used in one case, but the resulting polydipsia increased the incidence of regurgitation, resulting in recurrent episodes of aspiration pneumonia.