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Systemic histiocytosis in a Bernese mountain dog
Author(s) -
Brearley M. J.,
Dunn K. A.,
Smith K. C.,
Blunden A. S.
Publication year - 1994
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1994.tb03280.x
Subject(s) - medicine , chemosis , histiocyte , histopathological examination , infiltration (hvac) , histiocytosis , azathioprine , physical examination , dermatology , pathology , surgery , disease , physics , thermodynamics
Systemic histiocytosis was diagnosed at post mortem examination in a three‐year‐old Bernese mountain dog born in the United Kingdom. The dog presented with a progressive nodular skin disease, chemosis and periocular swelling occurring over six months. It was unresponsive to topical corticosteroids, antibiotics and oral azathioprine. Elective euthanasia was performed. Post mortem examination revealed extensive histiocytic infiltration of the skin, subcutis and skeletal muscles, particularly of the head.