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Effects of thiopentone and propofol on lower oesophageal sphincter and barrier pressure in the dog
Author(s) -
Waterman A. E.,
Hashim M. A.
Publication year - 1992
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1992.tb01046.x
Subject(s) - acepromazine , propofol , premedication , medicine , anesthesia , atropine , peristalsis , butorphanol , blood pressure , heart rate
The effects of thiopentone and propofol on oesophageal pressures were examined in 39 bitches. The dogs were premedicated with either atropine (n = 13), acepromazine maleate (n = 13) or a combination of atropine and acepromazine. Anaesthesia was induced with either thiopentone (15 dogs) or propofol (24 dogs), both given intravenously. Immediately following the induction of anaesthesia, gastric pressure and lower oesophageal sphincter pressure (LOSP) were measured and oesophageal barrier pressure determined. There were no significant differences attributable to the premedication regimens used but both LOSP and barrier pressure were significantly lower in the dogs anaesthetised with propofol compared to the animals given thiopentone (LOSP 12‐2 ± 4‐2 cm H 2 O propofol group versus 26‐8 ± 6‐5 cm H 2 O thiopentone group).