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A survey of the diagnosis and treatment of canine exocrine pancreatic insufficiency
Author(s) -
Hall E. J.,
Bond P. M.,
McLean C.,
Batt R. M.,
McLean L.
Publication year - 1991
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1991.tb00903.x
Subject(s) - medicine , exocrine pancreatic insufficiency , disease , antibiotics , gastroenterology , pancreas , surgery , microbiology and biotechnology , biology
A questionnaire was sent to veterinary surgeons who had diagnosed exocrine pancreatic insufficiency (EPI) by assay of low serum concentration of trypsin‐like immunoreactivity in 302 dogs. Two‐thirds of cases were German shepherd dogs, in which EPI was found equally in males and females. The disease was also diagnosed in 33 other breeds, most commonly in crossbreeds, spaniels, small terriers and collies, and was more common in females. Detailed replies on 160 cases were returned; 79 dogs were alive and 41 dead, with the remainder lost to long term follow‐up. The major reasons for death were euthanasia because of the cost, the prognosis, and failure to respond to treatment. An adequate response to treatment was obtained in 92 per cent of dogs. Uncoated preparations of pancreatic enzyme replacement were found to be more successful, and the use of dietary manipulation and antibiotics were frequently reported to be useful adjunctive therapies.