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Pulmonary alveolar proteinosis (phospholipoproteinosis) in a dog
Author(s) -
JEFFERIES A. R.,
DUNN J. K.,
DENNIS R.
Publication year - 1987
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1987.tb05987.x
Subject(s) - medicine , pulmonary alveolar proteinosis , pathological , radiography , pathology , lung , pulmonary surfactant , respiratory system , radiology , physics , thermodynamics
ABSTRACT This paper presents clinical, radiographic and pathological appearances in a case of pulmonary alveolar lipoproteinosis in a one‐year‐old Cocker Spaniel. This condition, well recognized in man appears not to have been reported previously as a spontaneous disease in the dog. The main features were insidious decreased exercise tolerance and increasing respiratory embarrassment. Radiographic lung changes were associated with filling of pulmonary alveoli with PAS‐positive lipoproteina‐ceous material. Inflammatory changes were minimal. The alveolar material consisted of excessive amounts of a substance that resembled surfactant.