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Two cases of IgA multiple myeloma in the dog
Author(s) -
DAY M. J.,
PENHALE W. J.,
McKENNA R. P.,
MILLS J. N.,
PASS D. A.
Publication year - 1987
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1987.tb05979.x
Subject(s) - paraproteins , medicine , multiple myeloma , pathological , alimentary tract , pathology , disease , immunology , antibody , monoclonal , monoclonal antibody
Clinical and laboratory findings are presented from two cases of canine IgA multiple myeloma. One of these animals presented with typical clinical and pathological changes including haematological abnormalities and skeletal lesions with secondary invasion of other organs. In contrast, the primary focus of disease in the second dog was the anterior alimentary tract and there were no skeletal changes. In this respect this second case was similar to the condition in man known as alpha chain disease. The two paraproteins differed in electrophoretic mobility.