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A comparison of calcium disodium ethylene diamine tetra‐acetate (CaEDTA) by oral and subcutaneous routes as a treatment of lead poisoning in dogs
Author(s) -
HAMIR A. N.,
SULLIVAN N. D.,
HANDSON P. D.,
BARR S.
Publication year - 1986
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1986.tb02241.x
Subject(s) - medicine , ethylene diamine , calcium , chelation , oral route , lead poisoning , lead (geology) , chelation therapy , pharmacology , oral administration , nuclear chemistry , organic chemistry , chemistry , thalassemia , geomorphology , psychiatry , geology
Four dogs accidentally poisoned by lead on a farm were used in a study to compare the efficacy of oral and injectable CaEDTA as chelating agent. Blood lead concentrations indicated that though both routes of administration were effective in reducing the lead levels, the injectable route appeared to reduce the lead level to within the normal range in a shorter period. The oral route, however, has the advantage that hospitalization is not required and it avoids the discomfort of numerous injections of the chelating agent.