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Cutaneous collagen nodules in a dog
Author(s) -
JONES B. R.,
ALLEY M. R.,
CRAIG A. S.
Publication year - 1985
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1985.tb02224.x
Subject(s) - medicine , pathology , histology , immunofluorescence , anti nuclear antibody , anatomy , antibody , autoantibody , immunology
A 16‐month‐old German short‐haired pointer was examined because of the development of multiple nodules (0.5‐3 cm diameter) in the skin of the head, back, sternum and limbs. The nodules were first noticed when the dog was 8 weeks of age. At no time did the animal show clinical signs of a systemic disease. Histology and electron microscopy revealed that the nodules were composed of irregular bundles of dense collagen fibres and the constituent fibrils had a distribution of diameters similar to that expected in normal skin. Immunofluorescence tests for immunoglobulin (IgG) and complement (C3) showed no deposits of these in the skin and the serum antinuclear antibody test was negative. It was concluded that the nodules were collagenous naevi.