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Diagnosis of canine exocrine pancreatic insufficiency by the assay of serum trypsin‐like immunoreactivity
Author(s) -
WILLIAMS DAVID A.,
BATT ROGER M.
Publication year - 1983
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1983.tb00404.x
Subject(s) - medicine , exocrine pancreatic insufficiency , radioimmunoassay , trypsin , gastroenterology , endocrinology , pancreas , enzyme , biochemistry , biology
A radioimmunoassay for canine serum trypsin‐like immunoreactivity (TLI) has been developed and evaluated for use in the diagnosis of exocrine pancreatic insufficiency (EPI). The maximum fasting TLI concentration in 14 dogs with EPI was 1.8 μg/l, compared with a minimum value of 7.0 μg/l in a control group of 75 dogs. The measurement of serum TLI therefore provides a sensitive test for the diagnosis of EPI in the dog.