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Clinical management of neoplasia – 2. Chemotherapy and immunotherapy
Author(s) -
OWEN L. N.,
BOSTOCK D. E.
Publication year - 1978
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1978.tb05477.x
Subject(s) - medicine , vincristine , prednisone , cyclophosphamide , chemotherapy , osteosarcoma , amputation , surgery , oncology , gastroenterology , pathology
ABSTRACT Chemotherapy for canine lymphosarcoma using vincristine, cytosine arabinoside, cyclophosphamide and prednisone produced a median remission time of 15 weeks and survival time of 6 months. Injections of BCG to dogs in remission was not beneficial. Following amputation for osteosarcoma, dogs were injected intravenously on several occasions with BCG vaccine. Of twenty dogs treated, eleven lived 6 months or more and eight lived over one year. The longest survival was 92 weeks.