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Hyperinsulinism in the dog due to pancreatic islet‐cell tumour: a report on three cases
Author(s) -
MATTHEEUWS D.,
ROTTIERS R.,
RIJCKE J.,
RICK A.,
SCHEPPER J.
Publication year - 1976
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1976.tb06963.x
Subject(s) - medicine , hyperinsulinism , islet , pancreas , insulin , endocrinology , plasma glucose , insulin resistance
Hypoglycaemia due to hyperinsulinism caused by an islet‐cell tumour, in three male Boxer dogs aged 9, 81/2 and 81/2 years respectively, is described. The clinical signs, the laboratory findings and the histological picture of the tumour of the pancreas which led to the diagnosis are discussed. The plasma immunoreactive insulin level (IRI), after 24‐hours fasting, or after stimulation by glucose, was elevated in only one case, but the ‘amended insulin‐glucose ratio’ was clearly increased in the other two cases, compared with normal dogs.