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Experimental acute gastric dilation and torsion in the dog‐1. Changes in biochemical and acid‐base parameters *
Author(s) -
WINGFIEL WAYNE E.,
CORNELIUS LARRY M.,
DeYOUNG DONALD W.
Publication year - 1975
Publication title -
journal of small animal practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 67
eISSN - 1748-5827
pISSN - 0022-4510
DOI - 10.1111/j.1748-5827.1975.tb05714.x
Subject(s) - medicine , creatinine , dilation (metric space) , torsion (gastropod) , endocrinology , gastroenterology , surgery , mathematics , combinatorics
Acute gastric dilation and torsion with dilation were produced in eleven dogs anaesthetized with halothane. Blood samples were taken during these procedures for biochemical analyses. Serum potassium did not change significantly, but there was a significant increase (p>0‐05) after release of the dilation with torsion. Renal function was impaired with significant increases (p > 0‐05) in the serum concentration of urea nitrogen, phosphorous, and creatinine. Evidence of cellular damage was reflected by a significant elevation (p>0‐05) in glutamic‐oxaloacetic transaminase activity. Serum glucose concentration increased significantly (p >0‐05) during experimental gastric dilation and dilation with torsion. Significant (p > 0‐05) acidosis occurred during both gastric dilation alone and gastric torsion with dilation. Changes in pCO 2 and pO 2 were generally not significant. Arterial HCO 3 values were significantly reduced (P>0‐05) 60 minutes after gastric dilation and continued to decrease during gastric torsion with dilation. It was deduced that gastric dilation with or without torsion was associated with metabolic acidosis.